Villa holiday rentals in Panama
Find and book unique villas on Airbnb
Top-rated villa rentals in Panama
Guests agree: These villas are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama villa rentals
Private villa rentals
Villa in Bocas del Toro
5.0 out of 5 average rating, 56 reviewsCasa del Mar - eco aqua villa
Villa in Saboga
5.0 out of 5 average rating, 7 reviewsSaboga: El Remanso Beachfront Entire Upper Level
Villa in Chame
4.97 out of 5 average rating, 58 reviewsOcean Pergola Villa (C10-PBB) 2 bed, 2 bath
Villa in Lagartero
5.0 out of 5 average rating, 12 reviewsPrivate Villa with private pool, in Santa Catalina
Villa in Bajo Boquete
4.94 out of 5 average rating, 63 reviewsSpacious Villa on a Coffee Farm 5 mins from town!
Villa in Las Escobas del Venado
4.95 out of 5 average rating, 21 reviewsBreathtaking Ocean Villa. Casa de Vida
Villa in Playa Venao
4.87 out of 5 average rating, 15 reviewsVilla Best Located in Blue | With Private Pool
Villa in PA
4.8 out of 5 average rating, 71 reviewsVilla Estrella in Playa Venao
Luxury villa rentals
Villa in Buenaventura, El Chirú
4.84 out of 5 average rating, 45 reviewsLake House | Pool | King Beds | Next to Beach Club
Villa in Playa Venao
4.98 out of 5 average rating, 61 reviewsCasa Aqua: Amazing beach front house - Playa Venao
Villa in Punta Chame
4.92 out of 5 average rating, 13 reviewsFREE NIGHT Amazing Beachfront Villa - Palm House
Villa in Río Hato
4.91 out of 5 average rating, 22 reviewsSecluded Villa in Buenaventura Golf and Resort
Villa in Bocas del Toro
5.0 out of 5 average rating, 16 reviewsCasa de Mono Luxury Open Air 3 Bedroom Apartment
Villa in Cañas
5.0 out of 5 average rating, 15 reviewsResidence Denter Tumas
Villa in Contadora Island
4.59 out of 5 average rating, 39 reviewsBeachfront Villa With Direct Beach Access & Pool
Villa in Juan Gallego
4.83 out of 5 average rating, 12 reviewsFantastic Villa in KasaKai
Villa rentals with a pool
Villa in Las Lajas
4.62 out of 5 average rating, 76 reviewsCORONADO VILLA VICTORIA
Villa in Las Lajas
5.0 out of 5 average rating, 4 reviewsCoronado Beach house pool and garden
Villa in Pedasí
4.86 out of 5 average rating, 14 reviewsDrone Pedasi Ranch - Beach Pool Folks Fest Fishing
Villa in Contadora Island
4.88 out of 5 average rating, 8 reviewsCheerful 2-bedroom villa with shared pool
Villa in El Chirú
4.86 out of 5 average rating, 22 reviewsFamily Beach House with Pool.
Villa in Boca Chica
4.95 out of 5 average rating, 81 reviewsSand Dollar Villa by the sea at Boca Chica Panama
Villa in Casamar
5.0 out of 5 average rating, 3 reviewsVilla La Valenciana by AcoModo @Casamar
Villa in Playa Venao
4.8 out of 5 average rating, 41 reviewsVilla Nomada - Barefoot Luxury 👑 Beach Front Villa
Destinations to explore
- Nature eco lodge rentals Panama
- Rentals with a sauna Panama
- Monthly Rentals Panama
- Loft rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Smoking-friendly rentals Panama
- Townhouse rentals Panama
- Chalet rentals Panama
- Boutique hotel rentals Panama
- Rentals with an accessible height bed Panama
- Rentals with beach access Panama
- Rentals with a fire pit Panama
- Cottage rentals Panama
- Pet-friendly rentals Panama
- Hotel rentals Panama
- Bungalow rentals Panama
- Rentals with breakfast Panama
- Rentals with a home theatre Panama
- Beach condo rentals Panama
- Rentals with a patio Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Rentals with a fireplace Panama
- Fitness-friendly rentals Panama
- Tree house rentals Panama
- Family-friendly rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with lake access Panama
- Bed and breakfasts Panama
- Tiny house rentals Panama
- House rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Kid-friendly rentals Panama
- Holiday home rentals Panama
- Waterfront rentals Panama
- Farmstay rentals Panama
- Guesthouse rentals Panama
- Rentals with a washing machine and dryer Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Island rentals Panama
- Beach house rentals Panama
- Rentals with a hot tub Panama
- Wheelchair accessible rentals Panama
- Apartment rentals Panama
- Condo rentals Panama
- Rentals with pools Panama
- Boat rentals Panama
- Villa rentals Panama City
- Villa rentals Playa Coronado
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom