Guesthouse holiday rentals in Greenville County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Greenville County guesthouses

Family-Friendly guesthouses

Top Guest favourite
Guesthouse in Travelers Rest
5 out of 5 average rating, 48 reviews

Travelers Rest Country Retreat Two miles to NGU

PeggyRating, 5 stars7 months ago
I can't say anything negative about Cliff and Mary's place. It is a gem. You watch horses graze on one side of the house and overlook a pond on the other side. Cliff and Mary are very responsive and go out of their way anticipating their guests needs, stocking the kitchen and fridge with snacks, coffee, cream, and other goodies. Any questions we had about the area were answered immediately. They are pleasant people that I would be glad to call new friends!
Guest favourite
Guesthouse in Pendleton
4.89 out of 5 average rating, 257 reviews

La Bella Farm

AdrienneRating, 5 stars2 weeks ago
We love staying here when we visit our son who is a student at Clemson. Very clean and excellent communication.
Top Guest favourite
Guesthouse in Liberty
4.93 out of 5 average rating, 194 reviews

Holly Hideaway! 10 Highway miles to Clemson U!

CliffRating, 5 stars2 months ago
Very informative and mindful host. Will certainly stay again!
Guest favourite
Guesthouse in Simpsonville
4.94 out of 5 average rating, 240 reviews

Private Suite in Downtown Simpsonville

TonyRating, 5 stars6 days ago
I can no longer count how many Airbnbs that I have stayed in. this one is well worth the cost. the location is fantastic if you want to walk to restaurants and/or bars at night. just far enough off the road to have a quiet night sleep. No smells at all inside and very clean. you do have to walk a half flight of stairs to get in but it lands onto a nice patio/porch with seating. I would definitely stay here again.
Guesthouse in Greenville
4.78 out of 5 average rating, 46 reviews

Quiet Guest Apartment in the Woods

JenniferRating, 5 stars30 months ago
Miranda's guest apartment was perfect for a long term stay. It was well equipped, neat, and ideally located with easy proximity to Paris Mountain State Park as well as downtown Greenville. Miranda was a wonderful host and prompt to respond the few times I needed something.
Top Guest favourite
Guesthouse in Greer
4.94 out of 5 average rating, 276 reviews

Executive Suite on a farm @GSP Airport

LandonRating, 5 stars1 week ago
Wonderful place! Nice people
Top Guest favourite
Private room in Pelzer
4.98 out of 5 average rating, 125 reviews

South Oaks Guesthouse

BethRating, 5 stars2 months ago
Diane's place was just what we needed for an overnight stay to watch an early bike race the next morning that took place right near by. The room was clean and the coffee cake was delicious, as described in many other reviews. The room was a bit smaller than expected for the price, but it was beautifully decorated and extremely comfortable. We would definitely stay again!

Guesthouses with a patio

Guest favourite
Guesthouse in Lyman
4.93 out of 5 average rating, 27 reviews

Budget Bliss: Cozy Elegance

KathyRating, 5 stars4 days ago
Christian’s place was just what we needed, yes it was basic, but that is all we needed for our quick trip to the area. It had a two burner cooktop, microwave, coffee pot and small refrigerator/freezer in the kitchen, small high top table for meals, small shower and a tv, AC, and comfortable queen size bed. And a cute porch which faced a wooded area, that was full of song birds for enjoying morning coffee. We were there basically on business, so we just needed a quiet place to sleep and recoup from the day’s activities. It was clean and comfortable for our short stay. Thanks Christian!
Guest favourite
Guesthouse in Greenville
4.89 out of 5 average rating, 66 reviews

Chic Studio with Private Deck

RosalindRating, 5 stars2 weeks ago
Very comfortable and well equipped space. I especially liked having the back porch. Host was very responsive. Definitely would stay here again.
Top Guest favourite
Guesthouse in Pelzer
4.97 out of 5 average rating, 36 reviews

Birdsong Bungalow-Family and Pet Friendly

RelissaRating, 5 stars4 days ago
Amy’s place was so welcoming and with a home like feel! She made sure every need was met for our family. We will be making this our yearly spot from now on!
Top Guest favourite
Guesthouse in Easley
5 out of 5 average rating, 44 reviews

Fun, cozy cottage for two w/games, deck in Easley

PeggyRating, 5 stars1 month ago
Very quiet and peaceful cottage on a beautiful lot. Watching the birds on the large deck was the highlight of the stay. The cottage is eclectic and fun, while roomy and functional. Shannon checked in several times and was very approachable with any needs. I would highly recommend this cottage and would definitely stay here again.
Guest favourite
Guesthouse in Greer
4.96 out of 5 average rating, 46 reviews

Sugar Creek Retreat

RobinRating, 5 stars1 day ago
I’ve stayed in several Airbnb’s and they were nice, but Kristen’s was the best by far. It was the most comfortable place to stay. She gets 2 thumbs up. If I had more thumbs she would get them too. Thank you for accepting us.
Superhost
Guesthouse in Taylors
4.78 out of 5 average rating, 40 reviews

Botanical Cottage

RenatoRating, 5 stars1 month ago
Mary was such a great host! She was very attentive and made sure we had everything we needed during stay. The space itself was very clean and comfortable and had all the amenities we needed (microwave, fridge, dishes, hot water, TV, extra towels, etc.). The bed was very comfortable to sleep in and the neighborhood was quiet and nice. We would definitely stay here again; thank you Mary!
Top Guest favourite
Guesthouse in Greenville
4.94 out of 5 average rating, 36 reviews

Tranquil 2BR Guest House on Pond by Furman

BaoRating, 5 stars2 weeks ago
Pictures don’t do the place justice! The home was so much more beautiful and spacious than we expected!
Guest favourite
Guesthouse in Piedmont
4.99 out of 5 average rating, 88 reviews

Shou-Sugi-Ban Retreat on the Saluda River

AlyssaRating, 5 stars1 week ago
Adorable place to stay. Great outdoor space! Place was very clean and amenities were great. Note there’s no TV so this is for relaxing and enjoying no distractions. Huge comfy bed! Good coffee maker with all the stuff you need. Definitely a nice place and I would stay again!! FYI…a little difficult to see the entrance to the house but easy if you pay attention to house numbers.

Guest house rentals with a washing machine and dryer

Guest favourite
Guesthouse in Greenville
4.98 out of 5 average rating, 99 reviews

The Spring Valley Retreat

LydaRating, 5 stars2 weeks ago
We had a wonderful stay here . We felt like we were at a true bed and breakfast .we brought our kids and they provided us with a few indoor toys that the boys loved and bubbles for the outside patio that they played with every morning while I had a cup of coffee. The hosts and the location were fantastic 10 min or less to everything we needed .
Top Guest favourite
Guesthouse in Fountain Inn
4.98 out of 5 average rating, 98 reviews

Upscale cottage in Downtown Fountain Inn

ChadRating, 5 stars3 weeks ago
This was my second visit here and I can’t wait for my third. The location is perfect, close to beautiful downtown Fountain Inn and just a short trip to downtown Greenville. Lisa is also an amazing host. Super responsive and stays ahead of any questions you might have.
Superhost
Guesthouse in Travelers Rest
4.78 out of 5 average rating, 18 reviews

Quiet King Two Bedrm House

CherieRating, 5 stars1 month ago
It was a nice space for a weekend at Furman. Close to downtown Travelers Rest. They have done a nice job renovated an older home. They were quick to answer any question. We had all our needs met. The backyard has a lot more potential, but it also looks like they have to clear some damage from the hurricane.
Guest favourite
Guesthouse in Taylors
4.97 out of 5 average rating, 138 reviews

Just off Main near Taylors Mill - Clean & Comfy

MikeRating, 5 stars2 weeks ago
This place is so clean and well taken care of. The attention to detail is evident. My son and I really appreciated the separate bedrooms and bathrooms. It was wonderful!
Superhost
Guesthouse in Greenville
4.97 out of 5 average rating, 37 reviews

Mod studio- loft, outdoor covered space & parking

DavidRating, 5 stars2 months ago
grate place easy to handle Tiffany grate person 100% satisfied
Top Guest favourite
Guesthouse in Duncan
5 out of 5 average rating, 62 reviews

Adorable renovated private house w/ parking.

LisaRating, 5 stars1 month ago
Great place to stay!
Guest favourite
Guesthouse in Greenville
4.94 out of 5 average rating, 72 reviews

Nishleigh's Nook - West End Downtown Greenville

MichaelRating, 5 stars1 week ago
Nicholas’s place is a terrific private space in a quiet location. Just a few minutes from downtown, but very easily accessible. The place was well appointed and comfortable.. We would definitely stay there again. Nicholas is a super host, very communicative, with good directions and attention to detail .
Top Guest favourite
Guesthouse in Mauldin
5 out of 5 average rating, 5 reviews

Beautiful guest house

ForrestRating, 5 stars1 month ago
We came as a couple to visit Family in Simpsonville and to ride the Swamp Rabbit Trail. Our stay was a "long weekend" so we wanted a place with room to spread out a bit as well as make easy meals/snacks/and have our cycling gear spread out. This home in Mauldin hit every mark on our list with flying colors! The place feels brand new, it is well back off the (quiet) street, has ample parking, and has a wonderful, very functional layout. The large, smart TV in the Livingroom was excellent for just casting from your phone, making it easy to chill before hitting the large, very comfy bed. Since it has 2 full bedrooms, we used the second bedroom to spread our stuff out - what a luxury :) !!! We got take-out the first evening we arrived, and there were MANY choice at-or-less-than 1 mile from the home. The value (price + experience) is EXCELLENT! We plan to stay here again when we come back for more visiting and cycling!

Destinations to explore