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Holiday houses in Clayton

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Top-rated holiday rentals in Clayton

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Home in St. Louis

4.92 out of 5 average rating, 191 reviews

Private Oasis w/hot tub

Wonderfully renovated 2 bedroom brick bungalow in highly desirable South city location. This home sits on a double lot, which has been completely renovated, featuring exterior shower with hot and cold, oversized hot tub, stamped concrete, gas fire pit, barbecue pit, and plenty of seating for up to 6 guests. Inside you’ll find home has been completely gut rehabbed featuring exposed brick walls, updated kitchen w/ center island. Two large bedrooms withking size beds, all new furnishings throughout

Guest favourite

Apartment in Soulard

4.94 out of 5 average rating, 115 reviews

Restful Relaxation Suite- Queen Bed- Hot Tub (327)

Soulard apartments aren't supposed to be this luxurious! If you are searching for a place to stay in Soulard and don't necessarily want the old historic, cobblestone, 1800's theme permeating through your walls, then look no further! We confidently boast the newest and nicest apartments in Soulard. - 0.5 Mi to Molly's in Soulard - 1.5 Mi to St. Louis Aquarium - 2.0 Mi to Gateway Arch - 2.2 Mi to The City Museum - 2.1 Mi to Ballpark Village - 1.6 Mi to Enterprise Center - 2.0 Mi to City Park!

Guest favourite

Home in Saint Charles

4.89 out of 5 average rating, 105 reviews

The Cardinal Nest A Cozy Cottage on Historic Main

The Cardinal nest is located directly on the cobblestone streets of St. Charles. the perfect place to lay your head if you are in town for a wedding, work, visiting family and friends or coming for a bike ride on the Katy Trail. The nest has 2 bedrooms, 1 full and 1 queen and will host 4 guests. The sweet little house hosts 2 units with the front unit being this listing and offers a washer and dryer in the unfinished basement. Guests must walk through one of the bedrooms to get to the bathroo

Guest favourite

Apartment in St. Louis

4.95 out of 5 average rating, 204 reviews

Historic Victorian, Safe neighborhood, 2nd Fl

First, check out all 4 of our private 5 Star listings that creatively combines the old with the new. If one is unavailable, check the others by going to “My Profile” and scrolling down until you see all 4. This Historic building; built in 1896 has changed missions through the years; From church, to merc. Trade, to grocery store; quite the history have graced these walls. You’ll love our safe, Southwest Gardens area; next to the famous “Hill” offers unmatched restaurant, shops, bakeries

Guest favourite

Home in Fenton

4.84 out of 5 average rating, 237 reviews

Fenton Oasis

Lovely fully furnished private basement >1800 sq ft single family home. Private heated pool is open and heated, kitchen, bathroom tub/shower, living room with fireplace TV, bedroom with egress full window and 2nd sleeping area. Many free parks with canoeing, hiking and biking trails nearby. Easy access to hwy 44. 270 & hwy 30, -restaurants -minutes from downtown St. Louis and airport. https://www.airbnb.com/highlights/131701267?s=39&unique_share_id=64fb0944-a8c7-40c1-bc83-6e65e70afeaf

Guest favourite

Home in Saint Charles

4.94 out of 5 average rating, 140 reviews

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

New Carpet! Adorable turn of the century home is located in Midtown St. Charles Historic District and sleeps 7. You won’t want to miss this St. Charles Charmer! Updated, fully stocked kitchen, dining room with Keurig coffee bar, living room w/75" SmartTV and plenty of seating throughout, SmartTV in 2 Bedrooms, 2 full bath, washer & dryer, outdoor gazebo w/table & chairs. Street & driveway parking. Close to area attractions: Historic Main Street, Ameristar Casino, & Lindenwood University.

Guest favourite

Home in Saint Charles

4.99 out of 5 average rating, 136 reviews

Charming 2/1 in St Charles Historic Main Street

Come relax and play! Half a block from historic Main Street in City of St Charles. This stay is everything you could want. Cozy, charming, private with outdoor area for seating and dinning table. Off-street parking, laundry. Go shopping in the historic downtown shops, go to concerts, casinos or just stay in and enjoy! Walk to restaurants and the Katy Trail! Come be our guest! Or stay in put and cook the kitchen has everything you need! We are a strictly non smoking stay, inside or outside.

Guest favourite

Home in Saint Charles

5 out of 5 average rating, 42 reviews

Caper on Kings

LUXURY 4BD/2BA Cottage with , 4 Seasons Room, GAME ROOM, & outdoor fire pit. You will be close to everything when you stay at this centrally-located place! Minutes form Historic St Charles, Walking distance to French town and local coffee shops, restaurants, and shopping. The high end home has plenty of space for everyone! Cook your favorite dinners in the COMPLETELY REMODELED high end kitchen, enjoy conversations around the table in the all window four seasons room or remodeled game room.

Guest favourite

Home in Tower Grove South

4.99 out of 5 average rating, 233 reviews

Spacious Family & Friends House Across From Tower Grove Park

Climb the front steps of a remarkably preserved craftsman period house with its exterior character intact. Inside is a modern space that's been remodeled top to bottom to a high level of quality and style, including a chef's kitchen and formal dining area. The house is the perfect place for large groups and families wanting plenty of space to spread out, relax and spend time together. Very kid friendly with porta cribs, highchairs, strollers and a baby monitor available for your use.

Guest favourite

Loft in Saint Charles

4.86 out of 5 average rating, 139 reviews

Main Street Historic Loft

Historic loft centrally located along the St. Charles riverfront, on the north end of Main Street and just south of Frenchtown. Enjoy Frontier Park, shops, restaurants, and night scene - all within walking distance. The newly renovated 2 bedroom and 2 full bathroom apartment can easily accommodate groups of six. The completely updated kitchen has granite countertops, stainless steel appliances, and a dishwasher. Convenient in-house washer and dryer available for extended stays.

Guest favourite

Home in South Hampton

5 out of 5 average rating, 31 reviews

Blair's Amazing House Sleeps 10 - 5 Beds - 2 Bath

Bring the family and welcome to Blairs House. Long Stays Welcome! - Stay for 30 days or more and SAVE! - Not available? Check our profile for over 30 listings in the area. 4 Bedrooms with 2 Full Bathrooms - One upstairs and One on the main level. Four Queen Beds and One King Bed. Cozy Living Room Dining Room seating for Eight Kitchen is fully stocked with all the essentials for casual cooking or thanksgiving dinner. Washer & dryer and Game Room located in Lower Level.

Guest favourite

Home in Tower Grove South

4.98 out of 5 average rating, 119 reviews

The Gateway Getaway

Stay in style at St. Louis's hottest listing! This home is perfect for group or family trips with 4 bedrooms, 6 beds, 3.5 bathrooms, 2 work-from-home spaces, a large kitchen, Peloton and the master closet of your dreams. Let the kids run free in the fenced in backyard or walk a few blocks to Tower Grove Park. This home is a few blocks from South Grand where you can visit the best restaurants, bars and shops St. Louis has to offer. Come enjoy St. Louis in luxury and convenience!

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Popular amenities for Clayton holiday rentals

Free parking on premises

Air conditioning

Stay near Clayton's top sights

Washington University in St. Louis34 locals recommend

Delmar Loop142 locals recommend

Saint Louis Zoo579 locals recommend

Saint Louis Art Museum431 locals recommend

The Pageant72 locals recommend

St. Louis Galleria146 locals recommend

Other great holiday rentals in Clayton

Home in Florissant

5 out of 5 average rating, 3 reviews

Florissant's Old Town Inn (3BR)

Guest favourite

Home in Ballwin

5 out of 5 average rating, 21 reviews

Perfect Getaway 3BR/3BA Home

Home in Central West End

4.88 out of 5 average rating, 93 reviews

Grand "La Chambre" in CWE | 5BR 4BA / ABODEbucks

Guest favourite

Home in St. Louis

5 out of 5 average rating, 30 reviews

3325: Bright Urban Comfort by JZ Vacation Rentals

Guest favourite

Home in Des Peres

4.91 out of 5 average rating, 67 reviews

Huge yard - 10 min walk to shops & restaurants

Guest favourite

Apartment in St. Louis

4.87 out of 5 average rating, 293 reviews

We do Italian STL style. Perfecto! Enjoy our NBHD!

Home in St. Louis

4.85 out of 5 average rating, 61 reviews

Modern Luxury w/Saltwater Pool / ABODEbucks

Guest favourite

Home in Lindenwood Park

4.87 out of 5 average rating, 713 reviews

Centrally Located Family Home - Park Like Yard

Quick stats about holiday rentals in Clayton

Total rentals
40 properties
Nightly prices starting at
$80 AUD before taxes and fees
Total number of reviews
1.5K reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace

Destinations to explore